August 23, 2017, 12:22 pm
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1 Philippine Peso = 0.07147 UAE Dirham
1 Philippine Peso = 2.19187 Albanian Lek
1 Philippine Peso = 0.03469 Neth Antilles Guilder
1 Philippine Peso = 0.33668 Argentine Peso
1 Philippine Peso = 0.02451 Australian Dollar
1 Philippine Peso = 0.03464 Aruba Florin
1 Philippine Peso = 0.03892 Barbados Dollar
1 Philippine Peso = 1.5756 Bangladesh Taka
1 Philippine Peso = 0.03242 Bulgarian Lev
1 Philippine Peso = 0.00733 Bahraini Dinar
1 Philippine Peso = 33.60051 Burundi Franc
1 Philippine Peso = 0.01946 Bermuda Dollar
1 Philippine Peso = 0.02651 Brunei Dollar
1 Philippine Peso = 0.13349 Bolivian Boliviano
1 Philippine Peso = 0.06121 Brazilian Real
1 Philippine Peso = 0.01946 Bahamian Dollar
1 Philippine Peso = 1.2483 Bhutan Ngultrum
1 Philippine Peso = 0.19907 Botswana Pula
1 Philippine Peso = 389.56996 Belarus Ruble
1 Philippine Peso = 0.03888 Belize Dollar
1 Philippine Peso = 0.02447 Canadian Dollar
1 Philippine Peso = 0.01877 Swiss Franc
1 Philippine Peso = 12.5721 Chilean Peso
1 Philippine Peso = 0.12979 Chinese Yuan
1 Philippine Peso = 58.11442 Colombian Peso
1 Philippine Peso = 11.13232 Costa Rica Colon
1 Philippine Peso = 0.01946 Cuban Peso
1 Philippine Peso = 1.82448 Cape Verde Escudo
1 Philippine Peso = 0.43076 Czech Koruna
1 Philippine Peso = 3.44814 Djibouti Franc
1 Philippine Peso = 0.1229 Danish Krone
1 Philippine Peso = 0.91224 Dominican Peso
1 Philippine Peso = 2.13275 Algerian Dinar
1 Philippine Peso = 0.25874 Estonian Kroon
1 Philippine Peso = 0.34501 Egyptian Pound
1 Philippine Peso = 0.45257 Ethiopian Birr
1 Philippine Peso = 0.01654 Euro
1 Philippine Peso = 0.03921 Fiji Dollar
1 Philippine Peso = 0.0151 Falkland Islands Pound
1 Philippine Peso = 0.01511 British Pound
1 Philippine Peso = 0.08543 Ghanaian Cedi
1 Philippine Peso = 0.87566 Gambian Dalasi
1 Philippine Peso = 172.07628 Guinea Franc
1 Philippine Peso = 0.14152 Guatemala Quetzal
1 Philippine Peso = 3.97957 Guyana Dollar
1 Philippine Peso = 0.15221 Hong Kong Dollar
1 Philippine Peso = 0.45349 Honduras Lempira
1 Philippine Peso = 0.12172 Croatian Kuna
1 Philippine Peso = 1.20354 Haiti Gourde
1 Philippine Peso = 5.01888 Hungarian Forint
1 Philippine Peso = 259.9533 Indonesian Rupiah
1 Philippine Peso = 0.07033 Israeli Shekel
1 Philippine Peso = 1.2483 Indian Rupee
1 Philippine Peso = 22.7087 Iraqi Dinar
1 Philippine Peso = 640.80562 Iran Rial
1 Philippine Peso = 2.08893 Iceland Krona
1 Philippine Peso = 2.47247 Jamaican Dollar
1 Philippine Peso = 0.01374 Jordanian Dinar
1 Philippine Peso = 2.12376 Japanese Yen
1 Philippine Peso = 2.00234 Kenyan Shilling
1 Philippine Peso = 1.33721 Kyrgyzstan Som
1 Philippine Peso = 79.92995 Cambodia Riel
1 Philippine Peso = 8.16852 Comoros Franc
1 Philippine Peso = 17.51314 North Korean Won
1 Philippine Peso = 22.14964 Korean Won
1 Philippine Peso = 0.00587 Kuwaiti Dinar
1 Philippine Peso = 0.01596 Cayman Islands Dollar
1 Philippine Peso = 6.48297 Kazakhstan Tenge
1 Philippine Peso = 161.09555 Lao Kip
1 Philippine Peso = 29.29364 Lebanese Pound
1 Philippine Peso = 2.98307 Sri Lanka Rupee
1 Philippine Peso = 2.22611 Liberian Dollar
1 Philippine Peso = 0.26095 Lesotho Loti
1 Philippine Peso = 0.05932 Lithuanian Lita
1 Philippine Peso = 0.01208 Latvian Lat
1 Philippine Peso = 0.02661 Libyan Dinar
1 Philippine Peso = 0.1842 Moroccan Dirham
1 Philippine Peso = 0.34588 Moldovan Leu
1 Philippine Peso = 1.01323 Macedonian Denar
1 Philippine Peso = 26.52267 Myanmar Kyat
1 Philippine Peso = 47.3633 Mongolian Tugrik
1 Philippine Peso = 0.15677 Macau Pataca
1 Philippine Peso = 7.02471 Mauritania Ougulya
1 Philippine Peso = 0.64623 Mauritius Rupee
1 Philippine Peso = 0.30142 Maldives Rufiyaa
1 Philippine Peso = 13.93073 Malawi Kwacha
1 Philippine Peso = 0.34414 Mexican Peso
1 Philippine Peso = 0.08344 Malaysian Ringgit
1 Philippine Peso = 0.25604 Namibian Dollar
1 Philippine Peso = 7.1006 Nigerian Naira
1 Philippine Peso = 0.58844 Nicaragua Cordoba
1 Philippine Peso = 0.1538 Norwegian Krone
1 Philippine Peso = 1.99066 Nepalese Rupee
1 Philippine Peso = 0.02661 New Zealand Dollar
1 Philippine Peso = 0.00749 Omani Rial
1 Philippine Peso = 0.01946 Panama Balboa
1 Philippine Peso = 0.06301 Peruvian Nuevo Sol
1 Philippine Peso = 0.06168 Papua New Guinea Kina
1 Philippine Peso = 1 Philippine Peso
1 Philippine Peso = 2.0504 Pakistani Rupee
1 Philippine Peso = 0.07069 Polish Zloty
1 Philippine Peso = 108.34793 Paraguayan Guarani
1 Philippine Peso = 0.07086 Qatar Rial
1 Philippine Peso = 0.07605 Romanian New Leu
1 Philippine Peso = 1.14343 Russian Rouble
1 Philippine Peso = 16.06149 Rwanda Franc
1 Philippine Peso = 0.07297 Saudi Arabian Riyal
1 Philippine Peso = 0.1508 Solomon Islands Dollar
1 Philippine Peso = 0.26075 Seychelles Rupee
1 Philippine Peso = 0.1296 Sudanese Pound
1 Philippine Peso = 0.15772 Swedish Krona
1 Philippine Peso = 0.02651 Singapore Dollar
1 Philippine Peso = 0.01511 St Helena Pound
1 Philippine Peso = 0.43211 Slovak Koruna
1 Philippine Peso = 145.94279 Sierra Leone Leone
1 Philippine Peso = 10.8776 Somali Shilling
1 Philippine Peso = 405.39601 Sao Tome Dobra
1 Philippine Peso = 0.17027 El Salvador Colon
1 Philippine Peso = 10.02102 Syrian Pound
1 Philippine Peso = 0.25583 Swaziland Lilageni
1 Philippine Peso = 0.64604 Thai Baht
1 Philippine Peso = 0.04749 Tunisian Dinar
1 Philippine Peso = 0.04262 Tongan paʻanga
1 Philippine Peso = 0.06846 Turkish Lira
1 Philippine Peso = 0.13124 Trinidad Tobago Dollar
1 Philippine Peso = 0.58973 Taiwan Dollar
1 Philippine Peso = 43.43258 Tanzanian Shilling
1 Philippine Peso = 0.49523 Ukraine Hryvnia
1 Philippine Peso = 69.99416 Ugandan Shilling
1 Philippine Peso = 0.01946 United States Dollar
1 Philippine Peso = 0.55517 Uruguayan New Peso
1 Philippine Peso = 80.17124 Uzbekistan Sum
1 Philippine Peso = 0.19409 Venezuelan Bolivar
1 Philippine Peso = 442.24558 Vietnam Dong
1 Philippine Peso = 2.01985 Vanuatu Vatu
1 Philippine Peso = 0.04832 Samoa Tala
1 Philippine Peso = 10.84141 CFA Franc (BEAC)
1 Philippine Peso = 0.05254 East Caribbean Dollar
1 Philippine Peso = 10.76455 CFA Franc (BCEAO)
1 Philippine Peso = 1.95213 Pacific Franc
1 Philippine Peso = 4.86379 Yemen Riyal
1 Philippine Peso = 0.25581 South African Rand
1 Philippine Peso = 100.98268 Zambian Kwacha
1 Philippine Peso = 7.04223 Zimbabwe dollar

The truth about Metformin

ONE of the most popular and very useful medications today worldwide is Metformin (Glucophage). This drug, whose molecular formula, C4H11N5, was first synthesized in 1929 and clinically introducedin the late 1950s by Jean Sterne, a French physician, who named it Glucophage, meaning glucose eater. In the United States, this drug was approved for type 2 diabetesby the FDA in 1994 and was marketed as Glucophage on March 3, 1995.

Evidence based clinical practice of today uses Metformin as the first-line oral drug for the treatment of type 2 diabetes mellitus, especially those who are overweight, according to the American Diabetes Association and the American College of Physicians.

In spite of its widespread global use and hundreds of millions benefiting from it, there are misleading and egregious assertions by some manufacturers of alternative herbal preparations for diabetes that Metformin is useless and dangerous. These are irresponsible claims in order for the uninformed and the gullible individuals to buy and use their products instead. These products, which have not been studied by the food and drug administration of the United States, the Philippines, or other countries, could be untested, unrefined, adulterated, contaminated, and are unsafe and possibly toxic in the long run.

How does Metformin work?

Contrary to some understanding, Metformin does not directly lower blood sugar like insulin does. Metformin acts to reduce the insulin resistance of the body cells to allow our own natural insulinto enter the cells to enable normal sugar metabolism. A significant number of type 2 diabetes suffer from insulin resistance that prevents insulin from entering the cells and doing its normal job, so the blood sugar goes up. Metformin reduces the resistance and improves the sensitivity of our body tissues in order for insulin to work more effectively. It also lowers the production of blood sugar in the liver. Again, on its own, Metformin does not cause hypoglycemia (low blood sugar).

Are ampalaya preparations as effective?

No. Ampalaya (bitter melon), a vegetable-fruit dish commonly prepared in Asian countries, has been found to lower blood sugar level a little, not significantly enough to be effective in controlling blood sugar level among diabetics. In spite of this limitation and lack of efficacy, ampalya preparations (pills, potions, lotions, teas) are on the shelves of many stores, claiming to lower blood sugar level, aimed at scamming the ignorant and gullible public. This is fraudulent because there have been reports of diabetics who stopped their prescribed medications and took these ampalaya preparations instead and have gone into diabetic comma. While eating ampalaya, a succulent dish, is a good idea for everyone, especially for diabetics, the use of the ampalaya preparations on the market as a substitute for (instead of) the prescription medication for diabetes is very dangerous and could be fatal.

What are the other uses of Metformin?

An amazing versatile drug, Metformin is also used for the treatment of polycystic ovary syndrome, and there are some limited suggestions that it may prevent cardiovascular disease and cancer complications of diabetes. More clinical studies are needed to confirm these. Its use is not linked to weight gain and higher risk of low blood sugar in contrast to the use of sulfonylureas for diabetes. Metformin also modestly reduces LDL (bad cholesterol) and triglycerides. Among obese non-diabetics, Metformin has been observed to be induce some weight loss. There is also a study that suggests Metformin be used as a second-line drug if clomifene treatment fails in the management of infertility among women.

Can Metformin prevent diabetes?

Among those with pre-diabetes, who are at risk of developing full-blown type 2 diabetes, treatment with Metformin has been found to reduce the chances of developing this metabolic disease. The same may be achieved with intensive regimented physical exercise done religiously, at least 20 minutes 5 days a week, as shown by the US Diabetes Prevention Program of lifestyle modification. This non-medication, exercise strategy, could lower the incidence of diabetes by 58 percent. Medical research on this continues to confirm these findings.

Does Metformin improve longevity?

This wonderful drug appears to increase longevity, at least in mice in the experimental laboratory, by a mean life span of 37.8 percent. Findings like this are extrapolated to be applicable among humans. There is scientific evidence that hyperglycemia (high blood sugar) and hyperinsulinemia (high insulin levels) are significant factors both in aging and development of cancer. The life prolonging effects of dieting (caloric restriction) has been attributed to decreasing IGF-1 (insulin growth factor-1), so eating less than maximal will reduce the need for the body to secrete more insulin and its level would go down, including body weight, and eventually in the long run slowing down aging and cancer risk. As my late teacher, Dr. Fe del Mundo, an internationally renowned pediatrician-scientist who lived to almost 100, still treating patients at age 94, stated, her secret to longevity was to push herself “away from the dining table less than full.”

What are the side-effects of Metformin?

Metformin is well-tolerated by most. Mild diarrhea is the usual initial side-effect that is transient, which stops after a day or so. Nausea, abdominal pains, flatulence have been reported but they are mild and temporary. If taken in overly large doses, it causes high blood lactic acid level. This drug is contraindicated among those with kidney or liver disease. Long term use of Metformin leads to vitamin B-12 deficiency, and increase the homocysteine level, which increases the risk for hardening of the arteries. Vitamin B-6, B-12, and Folic Acidmight be considered by the attending physician for these. Among pregnant women with gestational diabetes, insulin is the preferred treatment, although there is no clear evidence that Metformin causes harm among these patients. If the side-effects continue for days, which is not common, a medical consultation is advised.

Is it safe to self-medicate with Metformin?

As a rule, it is never safe to self-medicate or share medications with anyone, even with over-the-counter drugs, unless prescribed by a physician. Allergy and unexpected untoward reactions, side-effects, and unforeseen complication, sometimes fatal, can occur in some individuals. Metformin and all other medications must be taken under the guidance of a physician, who knows your personal circumstances and health.

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