April 22, 2018, 11:03 am
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1 Philippine Peso = 0.07053 UAE Dirham
1 Philippine Peso = 1.99923 Albanian Lek
1 Philippine Peso = 0.03418 Neth Antilles Guilder
1 Philippine Peso = 0.38677 Argentine Peso
1 Philippine Peso = 0.02467 Australian Dollar
1 Philippine Peso = 0.03418 Aruba Florin
1 Philippine Peso = 0.03841 Barbados Dollar
1 Philippine Peso = 1.59228 Bangladesh Taka
1 Philippine Peso = 0.03034 Bulgarian Lev
1 Philippine Peso = 0.00724 Bahraini Dinar
1 Philippine Peso = 33.62742 Burundi Franc
1 Philippine Peso = 0.0192 Bermuda Dollar
1 Philippine Peso = 0.02503 Brunei Dollar
1 Philippine Peso = 0.13175 Bolivian Boliviano
1 Philippine Peso = 0.06526 Brazilian Real
1 Philippine Peso = 0.0192 Bahamian Dollar
1 Philippine Peso = 1.26032 Bhutan Ngultrum
1 Philippine Peso = 0.18403 Botswana Pula
1 Philippine Peso = 384.48243 Belarus Ruble
1 Philippine Peso = 0.03837 Belize Dollar
1 Philippine Peso = 0.02421 Canadian Dollar
1 Philippine Peso = 0.01858 Swiss Franc
1 Philippine Peso = 11.41406 Chilean Peso
1 Philippine Peso = 0.12052 Chinese Yuan
1 Philippine Peso = 52.12791 Colombian Peso
1 Philippine Peso = 10.7778 Costa Rica Colon
1 Philippine Peso = 0.0192 Cuban Peso
1 Philippine Peso = 1.71039 Cape Verde Escudo
1 Philippine Peso = 0.39282 Czech Koruna
1 Philippine Peso = 3.39601 Djibouti Franc
1 Philippine Peso = 0.11551 Danish Krone
1 Philippine Peso = 0.94891 Dominican Peso
1 Philippine Peso = 2.1798 Algerian Dinar
1 Philippine Peso = 0.24262 Estonian Kroon
1 Philippine Peso = 0.33916 Egyptian Pound
1 Philippine Peso = 0.52276 Ethiopian Birr
1 Philippine Peso = 0.01551 Euro
1 Philippine Peso = 0.03865 Fiji Dollar
1 Philippine Peso = 0.01348 Falkland Islands Pound
1 Philippine Peso = 0.01349 British Pound
1 Philippine Peso = 0.08525 Ghanaian Cedi
1 Philippine Peso = 0.89975 Gambian Dalasi
1 Philippine Peso = 172.80584 Guinea Franc
1 Philippine Peso = 0.14089 Guatemala Quetzal
1 Philippine Peso = 3.95007 Guyana Dollar
1 Philippine Peso = 0.15072 Hong Kong Dollar
1 Philippine Peso = 0.45249 Honduras Lempira
1 Philippine Peso = 0.11491 Croatian Kuna
1 Philippine Peso = 1.24505 Haiti Gourde
1 Philippine Peso = 4.8093 Hungarian Forint
1 Philippine Peso = 264.60534 Indonesian Rupiah
1 Philippine Peso = 0.06739 Israeli Shekel
1 Philippine Peso = 1.26727 Indian Rupee
1 Philippine Peso = 22.73862 Iraqi Dinar
1 Philippine Peso = 806.60649 Iran Rial
1 Philippine Peso = 1.91031 Iceland Krona
1 Philippine Peso = 2.37565 Jamaican Dollar
1 Philippine Peso = 0.01361 Jordanian Dinar
1 Philippine Peso = 2.06171 Japanese Yen
1 Philippine Peso = 1.92145 Kenyan Shilling
1 Philippine Peso = 1.32194 Kyrgyzstan Som
1 Philippine Peso = 76.97331 Cambodia Riel
1 Philippine Peso = 7.61206 Comoros Franc
1 Philippine Peso = 17.28442 North Korean Won
1 Philippine Peso = 20.40042 Korean Won
1 Philippine Peso = 0.00575 Kuwaiti Dinar
1 Philippine Peso = 0.01575 Cayman Islands Dollar
1 Philippine Peso = 6.25043 Kazakhstan Tenge
1 Philippine Peso = 158.93989 Lao Kip
1 Philippine Peso = 28.9034 Lebanese Pound
1 Philippine Peso = 2.99693 Sri Lanka Rupee
1 Philippine Peso = 2.50451 Liberian Dollar
1 Philippine Peso = 0.22892 Lesotho Loti
1 Philippine Peso = 0.05855 Lithuanian Lita
1 Philippine Peso = 0.01192 Latvian Lat
1 Philippine Peso = 0.02543 Libyan Dinar
1 Philippine Peso = 0.17577 Moroccan Dirham
1 Philippine Peso = 0.31452 Moldovan Leu
1 Philippine Peso = 0.94968 Macedonian Denar
1 Philippine Peso = 25.52333 Myanmar Kyat
1 Philippine Peso = 45.86134 Mongolian Tugrik
1 Philippine Peso = 0.15521 Macau Pataca
1 Philippine Peso = 6.76013 Mauritania Ougulya
1 Philippine Peso = 0.64144 Mauritius Rupee
1 Philippine Peso = 0.29902 Maldives Rufiyaa
1 Philippine Peso = 13.70175 Malawi Kwacha
1 Philippine Peso = 0.35007 Mexican Peso
1 Philippine Peso = 0.07459 Malaysian Ringgit
1 Philippine Peso = 0.22915 Namibian Dollar
1 Philippine Peso = 6.87536 Nigerian Naira
1 Philippine Peso = 0.59554 Nicaragua Cordoba
1 Philippine Peso = 0.14884 Norwegian Krone
1 Philippine Peso = 2.01652 Nepalese Rupee
1 Philippine Peso = 0.02629 New Zealand Dollar
1 Philippine Peso = 0.00739 Omani Rial
1 Philippine Peso = 0.0192 Panama Balboa
1 Philippine Peso = 0.06176 Peruvian Nuevo Sol
1 Philippine Peso = 0.06241 Papua New Guinea Kina
1 Philippine Peso = 1 Philippine Peso
1 Philippine Peso = 2.21836 Pakistani Rupee
1 Philippine Peso = 0.06459 Polish Zloty
1 Philippine Peso = 106.04187 Paraguayan Guarani
1 Philippine Peso = 0.0699 Qatar Rial
1 Philippine Peso = 0.07223 Romanian New Leu
1 Philippine Peso = 1.16816 Russian Rouble
1 Philippine Peso = 16.22066 Rwanda Franc
1 Philippine Peso = 0.07202 Saudi Arabian Riyal
1 Philippine Peso = 0.14768 Solomon Islands Dollar
1 Philippine Peso = 0.25792 Seychelles Rupee
1 Philippine Peso = 0.34667 Sudanese Pound
1 Philippine Peso = 0.161 Swedish Krona
1 Philippine Peso = 0.02513 Singapore Dollar
1 Philippine Peso = 0.01349 St Helena Pound
1 Philippine Peso = 0.42646 Slovak Koruna
1 Philippine Peso = 146.53351 Sierra Leone Leone
1 Philippine Peso = 10.79316 Somali Shilling
1 Philippine Peso = 380.06338 Sao Tome Dobra
1 Philippine Peso = 0.16804 El Salvador Colon
1 Philippine Peso = 9.89015 Syrian Pound
1 Philippine Peso = 0.22917 Swaziland Lilageni
1 Philippine Peso = 0.599 Thai Baht
1 Philippine Peso = 0.04602 Tunisian Dinar
1 Philippine Peso = 0.04292 Tongan paʻanga
1 Philippine Peso = 0.07736 Turkish Lira
1 Philippine Peso = 0.12961 Trinidad Tobago Dollar
1 Philippine Peso = 0.56365 Taiwan Dollar
1 Philippine Peso = 43.7488 Tanzanian Shilling
1 Philippine Peso = 0.50259 Ukraine Hryvnia
1 Philippine Peso = 70.84694 Ugandan Shilling
1 Philippine Peso = 0.0192 United States Dollar
1 Philippine Peso = 0.54158 Uruguayan New Peso
1 Philippine Peso = 154.65719 Uzbekistan Sum
1 Philippine Peso = 1139.831 Venezuelan Bolivar
1 Philippine Peso = 437.43038 Vietnam Dong
1 Philippine Peso = 2.00538 Vanuatu Vatu
1 Philippine Peso = 0.04922 Samoa Tala
1 Philippine Peso = 10.16881 CFA Franc (BEAC)
1 Philippine Peso = 0.05185 East Caribbean Dollar
1 Philippine Peso = 10.16881 CFA Franc (BCEAO)
1 Philippine Peso = 1.83983 Pacific Franc
1 Philippine Peso = 4.79931 Yemen Riyal
1 Philippine Peso = 0.2292 South African Rand
1 Philippine Peso = 99.66391 Zambian Kwacha
1 Philippine Peso = 6.95026 Zimbabwe dollar

The truth about Metformin

ONE of the most popular and very useful medications today worldwide is Metformin (Glucophage). This drug, whose molecular formula, C4H11N5, was first synthesized in 1929 and clinically introducedin the late 1950s by Jean Sterne, a French physician, who named it Glucophage, meaning glucose eater. In the United States, this drug was approved for type 2 diabetesby the FDA in 1994 and was marketed as Glucophage on March 3, 1995.

Evidence based clinical practice of today uses Metformin as the first-line oral drug for the treatment of type 2 diabetes mellitus, especially those who are overweight, according to the American Diabetes Association and the American College of Physicians.

In spite of its widespread global use and hundreds of millions benefiting from it, there are misleading and egregious assertions by some manufacturers of alternative herbal preparations for diabetes that Metformin is useless and dangerous. These are irresponsible claims in order for the uninformed and the gullible individuals to buy and use their products instead. These products, which have not been studied by the food and drug administration of the United States, the Philippines, or other countries, could be untested, unrefined, adulterated, contaminated, and are unsafe and possibly toxic in the long run.

How does Metformin work?

Contrary to some understanding, Metformin does not directly lower blood sugar like insulin does. Metformin acts to reduce the insulin resistance of the body cells to allow our own natural insulinto enter the cells to enable normal sugar metabolism. A significant number of type 2 diabetes suffer from insulin resistance that prevents insulin from entering the cells and doing its normal job, so the blood sugar goes up. Metformin reduces the resistance and improves the sensitivity of our body tissues in order for insulin to work more effectively. It also lowers the production of blood sugar in the liver. Again, on its own, Metformin does not cause hypoglycemia (low blood sugar).

Are ampalaya preparations as effective?

No. Ampalaya (bitter melon), a vegetable-fruit dish commonly prepared in Asian countries, has been found to lower blood sugar level a little, not significantly enough to be effective in controlling blood sugar level among diabetics. In spite of this limitation and lack of efficacy, ampalya preparations (pills, potions, lotions, teas) are on the shelves of many stores, claiming to lower blood sugar level, aimed at scamming the ignorant and gullible public. This is fraudulent because there have been reports of diabetics who stopped their prescribed medications and took these ampalaya preparations instead and have gone into diabetic comma. While eating ampalaya, a succulent dish, is a good idea for everyone, especially for diabetics, the use of the ampalaya preparations on the market as a substitute for (instead of) the prescription medication for diabetes is very dangerous and could be fatal.

What are the other uses of Metformin?

An amazing versatile drug, Metformin is also used for the treatment of polycystic ovary syndrome, and there are some limited suggestions that it may prevent cardiovascular disease and cancer complications of diabetes. More clinical studies are needed to confirm these. Its use is not linked to weight gain and higher risk of low blood sugar in contrast to the use of sulfonylureas for diabetes. Metformin also modestly reduces LDL (bad cholesterol) and triglycerides. Among obese non-diabetics, Metformin has been observed to be induce some weight loss. There is also a study that suggests Metformin be used as a second-line drug if clomifene treatment fails in the management of infertility among women.

Can Metformin prevent diabetes?

Among those with pre-diabetes, who are at risk of developing full-blown type 2 diabetes, treatment with Metformin has been found to reduce the chances of developing this metabolic disease. The same may be achieved with intensive regimented physical exercise done religiously, at least 20 minutes 5 days a week, as shown by the US Diabetes Prevention Program of lifestyle modification. This non-medication, exercise strategy, could lower the incidence of diabetes by 58 percent. Medical research on this continues to confirm these findings.

Does Metformin improve longevity?

This wonderful drug appears to increase longevity, at least in mice in the experimental laboratory, by a mean life span of 37.8 percent. Findings like this are extrapolated to be applicable among humans. There is scientific evidence that hyperglycemia (high blood sugar) and hyperinsulinemia (high insulin levels) are significant factors both in aging and development of cancer. The life prolonging effects of dieting (caloric restriction) has been attributed to decreasing IGF-1 (insulin growth factor-1), so eating less than maximal will reduce the need for the body to secrete more insulin and its level would go down, including body weight, and eventually in the long run slowing down aging and cancer risk. As my late teacher, Dr. Fe del Mundo, an internationally renowned pediatrician-scientist who lived to almost 100, still treating patients at age 94, stated, her secret to longevity was to push herself “away from the dining table less than full.”

What are the side-effects of Metformin?

Metformin is well-tolerated by most. Mild diarrhea is the usual initial side-effect that is transient, which stops after a day or so. Nausea, abdominal pains, flatulence have been reported but they are mild and temporary. If taken in overly large doses, it causes high blood lactic acid level. This drug is contraindicated among those with kidney or liver disease. Long term use of Metformin leads to vitamin B-12 deficiency, and increase the homocysteine level, which increases the risk for hardening of the arteries. Vitamin B-6, B-12, and Folic Acidmight be considered by the attending physician for these. Among pregnant women with gestational diabetes, insulin is the preferred treatment, although there is no clear evidence that Metformin causes harm among these patients. If the side-effects continue for days, which is not common, a medical consultation is advised.

Is it safe to self-medicate with Metformin?

As a rule, it is never safe to self-medicate or share medications with anyone, even with over-the-counter drugs, unless prescribed by a physician. Allergy and unexpected untoward reactions, side-effects, and unforeseen complication, sometimes fatal, can occur in some individuals. Metformin and all other medications must be taken under the guidance of a physician, who knows your personal circumstances and health.

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